Active Pulmonary Tuberculosis Triggered by Interferon Beta-1b Therapy of Multiple Sclerosis: Four Case Reports and a Literature Review
نویسندگان
چکیده
منابع مشابه
Application of Interferon Beta-1b in Multiple Sclerosis
Recombinant interferon beta-1b (IFNβ-1b) was the first approved disease-modifying therapy for patients with multiple sclerosis (MS) by the world regulatory agencies for medical drugs and devices. IFNβ-1b significantly decreases the inflammatory component of MS but still has doubtable effect on the neurodegenerative component. This article appraises the beneficial effects of IFNβ-1b on clinical ...
متن کاملCutaneous and pulmonary sarcoidosis following treatment of multiple sclerosis with interferon-β-1b: a case report
INTRODUCTION Several cases of sarcoidosis following treatment with interferon-α have been reported in the literature, but those following interferon-β are very rare. We report the case of a patient with multiple sclerosis who developed pulmonary and cutaneous sarcoidosis following treatment with Betaseron® (interferon-β-1b). CASE PRESENTATION A 33-year-old Caucasian woman with a history of mu...
متن کاملNeutralizing antibodies (NABS) and interferon beta-1b therapy of multiple sclerosis.
Biological drugs that have a protein or peptide structure provide new and highly eff e c t i v e therapies for a number of conditions and diseases, but their prolonged use in patients gives rise to new problems and questions, amongst them the possible occurrence of neutralizing antibodies (Nabs). We discuss some aspects of this particular problem in relation to interferon-beta therapy of multip...
متن کاملReview of interferon beta-1b in the treatment of early and relapsing multiple sclerosis
Multiple sclerosis (MS) is the most common autoimmune illness of the central nervous system. For many years the inflammatory manifestations of MS were treated using only corticosteroids. Since the 1990s the results of several clinical trials with immunomodulatory agents have changed the therapeutic approach to this disease. Interferon beta (IFNbeta)-1b represents the pioneer of those therapies....
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ژورنال
عنوان ژورنال: Medicina
سال: 2020
ISSN: 1648-9144
DOI: 10.3390/medicina56040202